In the last decade the growth of the HIV prevalence in Iran among injecting drug users has shifted from ‘low prevalence’ to a ‘concentrated epidemic.’ According to UNAIDS, the Joint United Nations Programme on HIV/AIDS, one of the main challenges faced in Iran includes advocacy for stigma reduction. This guide is designed to help reduce stigmas faced in the workplace. The guide is designed to be taught be peer educators and includes strategies for peer education in addition to the HIV/Aids awareness curriculum. It also includes detailed information on the rights of workers who are HIV/AIDS positive. Originally designed for use in Trinidad and Tobago, this guide can be adopted in any country.